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August 20, 2008 Est 1999 Scotland's award-winning independent newspaper
New MRSA test ‘takes 10 minutes’
NHS hospitals to trial speedy screening process

A NEW system which enables patients to be screened for MRSA in just 10 minutes is set to undergo trials in the NHS.

The technology, developed in conjunction with experts at Strathclyde University, uses naturally occuring viruses that prey on bacteria as a sensor to detect for the superbug. Swabs taken from patients are read on a machine - similar to those used in bank ATMs - which nurses on wards can directly access, instead of having to send tests to a laboratory.

The firm behind the system claims it will allow staff to identify quickly the estimated 80% of people who are not carrying MRSA (methicillin resistant staphylococcus aureus) and allow them to concentrate infection control measures on high-risk patients.

Although scientists are still working on the final stages of the development of the system, it is anticipated that clinical trials will begin later this year in up to four NHS hospitals across the UK, including one in Scotland.

Experts have repeatedly called for widespread screening to be introduced to tackle the high rates of MRSA in hospitals across the UK, an approach which has proved successful in other countries such as Holland. Health watchdog body NHS Quality Improvement Scotland is currently assessing if some form of MRSA screening should be introduced north of the Border.

David Stokes, director of sales and marketing at Blaze Venture Technologies, the company developing the test, said a major advantage of the new system was the speed of results compared with the normal NHS tests.

"You get the initial screening result in 10 minutes, directly at the point of care, as opposed to two, three or four days for conventional culture testing," he said. "That allows for better patient management, as you can separate people who are negative from people who are carriers of staphylococcus aureus, which is the family of bugs that includes MRSA.

"This means that staff can focus their barrier precautions - such as gloves, gowns, handwashing - on a limited number of patients who are known to be carriers of staphylococcus aureus."

Stokes added that while the pricing of the system would not be known until the clinical trials were underway, it was anticipated it would be "highly cost effective".

The system harnesses natural bacteriophages - viruses which are harmless to humans but attack and destroy bacteria. They have been as viewed as possible weapons against bacteria since the 1920s, but one major problem has been that they rapidly become inactive unless they remain waterborne.

However, scientists at Strathclyde University have developed technology which enables them to survive for around two weeks in a dry atmosphere. Inventor Dr Mike Mattey, from the university's institute for pharmacy and biomedical sciences, said: "What we have developed is a means of immobilising them onto surfaces and one of the effects of that is to make them much more stable."

The new MRSA test involves taking a swab from the patient and wiping it onto a card coated with a light-emitting bacteriophage. The virus quickly multiplies when MRSA is present and can be detected by the machine, allowing staff to determine if the patient is potentially carrying the infection in as little as 10 minutes.

Dr Dugald Baird, a consultant microbiologist at Hairmyres Hospital, Lanarkshire, said that the "novel approach" of the system was welcome, but cautioned that speedy testing was not necessarily viewed as top priority in tackling the superbug.

"When it comes to predicting MRSA control in a hospital setting, there are one or two people looking at mathematical models and rapid diagnostic methods don't feature highly on the list," he said. "More important is the availability of isolation facilities, putting patients that you think are at risk of being MRSA carriers safely into a single room before you know the results of screening them."

Derek Butler, chairman of patient group MRSA Action UK, questioned whether cost issues would deter hospitals from using such new technologies.

"Anything that helps to reduce infections is welcome and costs should not come into it," he said. "We believe all tools should be used in the fight to prevent infections being spread - technologies, hand hygiene and cleanliness; everything will play its part."

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Posted by: derek butler, kirkham on 9:29pm Sat 26 May 07
At MRSA Action UK we believe that cost should not come in to the equation when we come to fighting infections in our hospitals. We have in our Charity had people approach us in respect to thier loved ones having to wait up to 5 days for the results of swabs being taken to se if they are infected with a Hospital Associated Infection sometimes over the weekend when some hospital labs do not work. This time lag is far to long when you have a patient who is infected with something as serious as MRSA. We have stories from people who contact us who tell us that their loved ones,or if it is someone who has been infected themselves, were the delay in identifying the infection has left them feeling very poorly, and in some circumstances even meant that they have died.
If we have the technology to help identify that a person is either colonised or infected with an infection such as MRSA then that technology should be incorporated in the battle to fight Healthcare Infections. However the first line of defense in preventing a person from contracting a Healthcare infection should always be preventative and in doing so reduce the pain and suffering that patients and their families have to bare.
There is no subsitute for good infection control using Hand Hygiene, Clean Hospital wards and proper systems of work that prevent the Healthcare Infections being spread within the hospital enviroment in the first place. Infection control is everyones business using what ever tools are available and not at the cheapest cost available.
You cannot put a price on human life especially when you can prevent that life from being lost.
Derek Butler, Chair of the Charity MRSA Action UK.
Posted by: Mavis Law, Cheshire on 11:07am Sun 27 May 07
Cash spent on early detection of MRSA is surely better than the cost of beds being occupied for weeks rather than days and the cost in many lives lost and human suffering. Now that there is this technology the N.H.S must implement its use if we are to ever be free of these avoidable infections and bring our hospitals to a standard on a par with the Netherlands.I watched my 32yr old Son,Colin, die from MRSA and if this new technology was available then he would still be with us today ! I agree with everything that Derek Butler has said and that Cost should not come into the equation! Mavis Law MRSA Action UK.
Posted by: steve on 11:42am Mon 22 Oct 07
I have been told by a very knowledgeable friend who has brilliant sons and a daughter who work in the relative fields of microbiology that natural bacteriophages have been around and aparently used in certain parts of the world for years and mrsa can and is cured like we would cure a common cold. If so why is it not common knowledge and used over for curing mrsa and not just detecting it?? I think we will see and hear about bacteriophages alot in future and Julian believes will one day soon be the way forward with medicine as a whole and not just to check for an infection but to cure them. He also believes that the alcohol hand cleaner that the hospitals put out to use(NOT MAKE PEOPLE USE IT!!) wouldn't kill the staphylococcus aureus anyway. Sometimes I feel the whole system (NOT including all the great caring staff) is all about penny pinching and putting on a show that we are cared for. Why the smoking ban for instance?? Agree or not with it but was it because the cost of healthcare was over riding the income from the tax gained through making people DIE early with smoking related diseases?? Not to mention the years of lost tax through early death or retirement due to illness. If so no thought for the public again just the governments pocket. BTW. My interest in being here is that my 7tr old daughter Kt has a blood infection and we r awaiting tests. All negative so far but mrsa is as possible as anything as she is in and out of hospital quite alot with other hormone problems. I have seen with my own eyes incompetence in the NHS and I would rather be one step ahead than behind. Last thing. Julian believes we could get on a plane tomorrow and go see a doctor abroad who would cure mrsa with bacteriophages easily. Does anyone know about this?????????? Is it true and that easy????
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